测试环境上配置主从的时候：
CHANGE MASTER TOMASTER_HOST='10.30.xx.xxx',MASTER_USER='repl',MASTER_PASSWORD='123456',MASTER_PORT=3306,MASTER_LOG_FILE='mysql-bin.000027',MASTER_LOG_POS=4, MASTER_CONNECT_RETRY=10;
ERROR 1794 (HY000): Slave is not configured or failed to initialize properly. You must at least set --server-id to enable either a master or a slave. Additional error messages can be found in the MySQL error log.
查看主从的配置文件都指定了server_id,然后查看err-log
2018-05-23T02:23:46.047520Z 0 [ERROR] Native table 'performance_schema'.'status_by_thread' has the wrong structure
2018-05-23T02:23:46.047537Z 0 [ERROR] Native table 'performance_schema'.'status_by_user' has the wrong structure
2018-05-23T02:23:46.047554Z 0 [ERROR] Native table 'performance_schema'.'global_status' has the wrong structure
2018-05-23T02:23:46.047571Z 0 [ERROR] Native table 'performance_schema'.'session_status' has the wrong structure
2018-05-23T02:23:46.047588Z 0 [ERROR] Native table 'performance_schema'.'variables_by_thread' has the wrong structure
2018-05-23T02:23:46.047605Z 0 [ERROR] Native table 'performance_schema'.'global_variables' has the wrong structure
2018-05-23T02:23:46.047622Z 0 [ERROR] Native table 'performance_schema'.'session_variables' has the wrong structure
2018-05-23T02:23:46.047830Z 0 [Note] /usr/local/mysql/bin/mysqld: ready for connections.
Version: '5.7.21-log' socket: '/tmp/mysql.sock' port: 3316 MySQL Community Server (GPL)
2018-05-23T02:23:46.980770Z 0 [Note] InnoDB: Buffer pool(s) load completed at 180523 10:23:46
解决：./mysql_upgrade -h 10.30.x.x -umha -p'123456' -P 3316 --force socket=/tmp/mysql.sock
Running queries to upgrade MySQL server.
Checking system database.
mysql.columns_priv OK
mysql.dbOK
mysql.dml_health_check OK
mysql.engine_cost OK
mysql.eventOK
mysql.failover_infoOK
mysql.func OK
mysql.general_log OK
mysql.gtid_executedOK
mysql.ha_health_check OK
mysql.help_categoryOK
mysql.help_keyword OK
mysql.help_relationOK
mysql.help_topicOK
mysql.innodb_index_statsOK
mysql.innodb_table_statsOK
mysql.ndb_binlog_index OK
mysql.pluginOK
mysql.proc OK
mysql.procs_privOK
mysql.proxies_priv OK
mysql.rds_table_checksums OK
mysql.server_cost OK
mysql.servers OK
mysql.slave_master_infoOK
mysql.slave_relay_log_info OK
mysql.slave_worker_infoOK
mysql.slow_log OK
mysql.tables_priv OK
mysql.time_zoneOK
mysql.time_zone_leap_secondOK
mysql.time_zone_nameOK
mysql.time_zone_transition OK
mysql.time_zone_transition_typeOK
mysql.user OK
Upgrading the sys schema.
Checking databases.
card_center.system_cacheOK
card_center.system_session OK
然后重启一下mysql就ok了。

mysql_upgrade升级的时候，检查不兼容的表，更新grant表；